Estudio comparativo de plantas hepatoprotectoras de origen Chino y Peruano
Date
2017-09-01
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Abstract
Establecer las diferencias y semejanzas entre las plantas hepatoprotectoras de origen chino y peruano. Reconocer los metabolitos secundarios responsables del efecto hepatoprotector. Métodos: Tamizaje fitoquímico y cromatografía en capa fina (CCF). Resultados: Los metabolitos secundarios hallados con mayor frecuencia entre los extractos hidroalcohólicos de las plantas hepatoprotectoras chinas y peruanas identificados en el tamizaje fitoquímico fueron de aproximadamente 12 por ciento derivados terpénicos (cadenas cíclicas), 10 por ciento flavonoides y 9 por ciento alcaloides. Los Rf hallados en la CCF entre las plantas hepatoprotectoras chinas fueron: 0.45 derivados terpénicos (marrón), 0.30 glucosa (pardo oscuro), 0.35 taninos (grises), 0.50 flavonoides (verde azulado), 0.67 curcumina (amarillo-verde). Los Rf hallados en la CCF entre las plantas hepatoprotectoras peruanas fueron: 0.30 alcaloides (café), 0.98 derivados terpénicos (verde oscuro), 0.60 flavonoides (amarillo oscuro), 0.55-0.64 glicósidos amargos (violeta oscuro/ fluorescente), 0.57 flavonoides (fluorescente). Conclusiones: Se obtuvieron semejanzas en las concentraciones de sus metabolitos secundarios de las plantas hepatoprotectoras chinas y peruanas verificando la existencia de al menos 12 por ciento de derivados terpénicos (cadenas cíclicas), 10 por ciento flavonoides, 9 por ciento alcaloides, 8 por ciento carbohidratos, 6 por ciento taninos, 6 por ciento saponinas, 4 por ciento cumarinas y 4 por ciento antraquinonas aproximadamente y también se encontraron semejanzas con respecto a la tipología de plantas hepatoprotectoras chinas y peruanas verificando la existencia de al menos 28 por ciento amarga, 16 por ciento tibia, 16 por ciento fría y 12 por ciento dulce aproximadamente. Los tipos de metabolitos secundarios identificados mediante el tamizaje fitoquímico y la cromatografía en capa fina de cada una de las plantas fueron derivados terpénicos (cadenas cíclicas), flavonoides y glicósidos amargos que tienen relevante importancia, ya que a estos metabolitos secundarios se les atribuye el efecto hepatoprotector de las plantas en estudio.
To establish differences and similarities between hepatoprotective plants of Chinese and Peruvian origin. Recognize the secondary metabolites responsible for the hepatoprotective effect. Methods: Phytochemical screening and thin layer chromatography (TLC). Results: The most frequently found secondary metabolites among the hydroalcoholic extracts of the Chinese and Peruvian hepatoprotective plants identified in phytochemical screening were approximately 12 percent terpenic derivatives (cyclic chains), 10 percent flavonoids and 9 percent alkaloids. The Rf found in TLC among Chinese hepatoprotective plants were: 0.45 terpenic derivatives (brown), 0.30 glucose (dark brown), 0.35 tannins (gray), 0.50 flavonoids (blue-green), 0.67 curcumin (yellow-green). The Rf found in TLC among Peruvian hepatoprotective plants were: 0.30 alkaloids (coffee), 0.98 terpenic derivatives (dark green), 0.60 flavonoids (dark yellow), 0.55-0.64 bitter glycosides (dark violet / fluorescent), 0.57 flavonoids (fluorescent). Conclusions: Similarities were found in the concentrations of their secondary metabolites of the Chinese and Peruvian hepatoprotective plants, verifying the existence of at least 12 percent of terpene derivatives (cyclic chains), 10 percent flavonoids, 9 percent alkaloids, 8 percent carbohydrates, 6 percent tannins, 6 percent saponins, 4 percent coumarins and 4 percent anthraquinones and similarities were also found with respect to the typology of the Chinese and Peruvian hepatoprotective plants, verifying the existence of at least 28 percent bitter, 16 percent warm, 16 percent cold and 12 percent sweet approximately. The types of secondary metabolites identified by phytochemical screening and thin layer chromatography of each plants were terpene derivatives (cyclic chains), flavonoids and bitter glycosides that have relevant importance, since these secondary metabolites are attributed the hepatoprotective effect of the plants under study.
To establish differences and similarities between hepatoprotective plants of Chinese and Peruvian origin. Recognize the secondary metabolites responsible for the hepatoprotective effect. Methods: Phytochemical screening and thin layer chromatography (TLC). Results: The most frequently found secondary metabolites among the hydroalcoholic extracts of the Chinese and Peruvian hepatoprotective plants identified in phytochemical screening were approximately 12 percent terpenic derivatives (cyclic chains), 10 percent flavonoids and 9 percent alkaloids. The Rf found in TLC among Chinese hepatoprotective plants were: 0.45 terpenic derivatives (brown), 0.30 glucose (dark brown), 0.35 tannins (gray), 0.50 flavonoids (blue-green), 0.67 curcumin (yellow-green). The Rf found in TLC among Peruvian hepatoprotective plants were: 0.30 alkaloids (coffee), 0.98 terpenic derivatives (dark green), 0.60 flavonoids (dark yellow), 0.55-0.64 bitter glycosides (dark violet / fluorescent), 0.57 flavonoids (fluorescent). Conclusions: Similarities were found in the concentrations of their secondary metabolites of the Chinese and Peruvian hepatoprotective plants, verifying the existence of at least 12 percent of terpene derivatives (cyclic chains), 10 percent flavonoids, 9 percent alkaloids, 8 percent carbohydrates, 6 percent tannins, 6 percent saponins, 4 percent coumarins and 4 percent anthraquinones and similarities were also found with respect to the typology of the Chinese and Peruvian hepatoprotective plants, verifying the existence of at least 28 percent bitter, 16 percent warm, 16 percent cold and 12 percent sweet approximately. The types of secondary metabolites identified by phytochemical screening and thin layer chromatography of each plants were terpene derivatives (cyclic chains), flavonoids and bitter glycosides that have relevant importance, since these secondary metabolites are attributed the hepatoprotective effect of the plants under study.
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Keywords
Tamizaje fitoquímico, Cromatografía, Metabolitos secundarios, Extractos hidroalcohólicos, Phytochemical screening, Chromatography, Secondary metabolites, Hydroalcoholic extracts